Personalised Cancer Medicine Flashcards 2025


Standard

Recommended

Currently not recommended
- EGFR
- ALK
- ROS1
- PDL-1
- RET*
- NTRK*
- KRAS y MET*
- BRAF V600
- NGS**
- HER2
- NRG1
** in biopsies with little sample; Approved in the USA as accompanying diagnosis of EGFR and ALK inhibitors
The Recommended category is based on currentrecommendations by EMEA and FDA.
References:
2. Colomer R, Mondejar R, Romero-Laorden N et al,. When should we order a next generation sequencing test in a patient with cancer? EClinicalMedicine. 2020 Jul 31;25:100487. doi: 10.1016/j.eclinm.2020.100487.
3. Mosele F, Remon J, Mateo J, et al. Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group. Ann Oncol. 2020 Nov;31(11):1491- 1505. doi: 10.1016/j.annonc.2020.07.014.
4. https://www.accessdata.fda.gov/cdrh_docs/pdf17/P170019S