Personalised Cancer Medicine Flashcards 2022
Standard
Recommended
Currently not recommended
- BRAF
- KIT*
- NRAS
- GNAQ/GNA11
- PTEN
- MITF
- CDKN2A
- MHC-II
- Tumor mutational burden
The Recommended category is based on currentrecommendations by EMEA and FDA.
References:
1. Martín-Algarra S, Fernández-Figueras MT, López-Martín JA, at al; Spanish Society of Pathology; Spanish Society of Medical Oncology. Guidelines for biomarker testing in metastatic melanoma: a National Consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology. Clin Transl Oncol. 2014 Apr;16(4):362-73. doi: 10.1007/s12094-013-1090-5.
2. Scherrer E, Rau R, Lorenzi M, Shui I, Townson S, Larkin J. Systematic literature review for the association of biomarkers with efficacy of anti-PD-1 inhibitors in advanced melanoma. Future Oncol. 2021 Mar 30. doi: 10.2217/fon-2021-0154.
3. Mao L, Dai J, Cao Y, et al. Palbociclib in advanced acral melanoma with genetic aberrations in the cyclin-dependent kinase 4 pathway. Eur J Cancer. 2021 Mar 23;148:297-306. doi: 10.1016/j.ejca.2021.02.021.